Disease: Muscle Spasticity
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WDR45 Q9Y484 WD repeat domain 45 0.99 0.647 0.423
VCP P55072 valosin containing protein 1.00 0.469 0.923
VAPB O95292 VAMP associated protein B and C Transporter 0.58 0.666 0.423
UNC13A Q9UPW8 unc-13 homolog A 1.00 0.705 0.423
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
TYROBP O43914 transmembrane immune signaling adaptor TYROBP 0.20 0.573 0.769
TUBB4A P04350 tubulin beta 4A class IVa Cellular structure 0.11 0.608 0.615
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
TBP P20226 TATA-box binding protein Transcription factor 1.5E-02 0.552 0.846
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TAF2 Q6P1X5 TATA-box binding protein associated factor 2 Enzyme 2.6E-03 0.743 0.308
TAF15 Q92804 TATA-box binding protein associated factor 15 Nucleic acid binding 0.17 0.626 0.500
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577
SURF1 Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 1.6E-13 0.578 0.654
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SPTBN2 O15020 spectrin beta, non-erythrocytic 2 9.9E-05 0.619 0.731
SPR P35270 sepiapterin reductase 4.3E-02 0.631 0.654
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
SPG16 spastic paraplegia 16 (complicated, X-linked recessive) 0.722 0.423
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538